Name | 6-OHDA |
Synonyms | 6-OHDA 6-HYDROXYDOPAMINE HBR 2,4,5-Trihydroxyphenethylamine 6-HYDROXYDOPAMINE HYDROBROMIDE 2,5-DIHYDROXYTYRAMINE HYDROBROMIDE 2,4,5-TRIHYDROXYPHENETHYLAMINE HYDROBROMIDE 2,4-benzenetriol,5-(2-aminoethyl)-hydrobromide 2-(2,4,5-TRIHYDROXYPHENYL)ETHYLAMINE HYDROBROMIDE |
CAS | 636-00-0 |
EINECS | 211-247-0 |
InChIKey | MLACDGUOKDOLGC-UHFFFAOYSA-N |
Molecular Formula | C8H12BrNO3 |
Molar Mass | 250.09 |
Melting Point | 216-220°C(lit.) |
Solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
Appearance | solid |
Color | tan to brown |
BRN | 3713280 |
Storage Condition | -20°C |
Stability | Hygroscopic, Light Sensitive |
MDL | MFCD00012894 |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
RTECS | DC4600000 |
FLUKA BRAND F CODES | 3-10 |
Reference Show more | 1. Jin Wenyu, Qin Xiaoyun, Cheng Zijuan, et al. Effect of superior mesenteric vein injection of 6-OHDA on blood glucose in rats [J]. Basic medical Forum, 2018, 04(v.22;No.520):44-46. 2. Ning Baile, Zhang Qinxin, Deng Minzhen, et al. Β-asarone reduces the dose of madopar in PD model rats [J]. Journal of Guangzhou University of Traditional Chinese Medicine, 2019 036(006):889-896. 3. Huang Yijian, Jiang Feng, Luo Zhanyuan, etc. Effect of wushenxingnao decoction on 6-hydroxydopamine induced Parkinson's disease in rats [J]. Chinese Journal of new drugs, 2019, 28(04):99-104. 4. Li Min Chang Xue Hui Zhang Liang Zhi, etc. Comparative analysis of Parkinson's disease rat model established by injecting 6-hydroxydopamine at different sites [J]. Laboratory animal and comparative medicine 2018 v.38(04):20-25. 5. [IF = 6.023] Maiquan Li et al."Acteoside protection agents against 6-OHDA-induced dopamine logic neuron via Nrf2-ARE signaling pathway." Food Chem Toxicol. 2018 Sep;119:6 |